Andrew Holmes Selected Research

Excitatory Amino Acid Transporter 1 (Glutamate Aspartate Transporter 1)

5/2009	Assessment of glutamate transporter GLAST (EAAT1)-deficient mice for phenotypes relevant to the negative and executive/cognitive symptoms of schizophrenia.
11/2008	Loss of glial glutamate and aspartate transporter (excitatory amino acid transporter 1) causes locomotor hyperactivity and exaggerated responses to psychotomimetics: rescue by haloperidol and metabotropic glutamate 2/3 agonist.

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Andrew Holmes Research Topics

Disease

12	Anxiety Disorders (Anxiety Disorder) 01/2020 - 02/2002
7	Hypothermia 01/2022 - 10/2006
6	Alcoholism (Alcohol Abuse) 03/2017 - 09/2008
5	Ataxia (Dyssynergia) 01/2022 - 08/2008
5	Wounds and Injuries (Trauma) 10/2020 - 01/2007
5	Schizophrenia (Dementia Praecox) 10/2013 - 11/2008
3	Mood Disorders (Mood Disorder) 01/2019 - 01/2015
3	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2019 - 06/2006
2	Neoplasms (Cancer) 01/2022 - 04/2006
2	Thrombosis (Thrombus) 01/2021 - 08/2008
2	Inflammation (Inflammations) 01/2021 - 04/2008
2	Myocardial Infarction 09/2017 - 02/2013
2	Infarction (Infarctions) 09/2017 - 04/2015
2	Hyperglycemia 06/2015 - 10/2005
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 06/2015 - 04/2015
2	Memory Disorders (Memory Loss) 06/2015 - 12/2009
2	Cognitive Dysfunction 06/2015 - 01/2009
2	Stroke (Strokes) 04/2015 - 04/2012
2	Infections 01/2015 - 02/2013
2	Psychotic Disorders (Schizoaffective Disorder) 03/2012 - 12/2010
1	Atherosclerosis 01/2021
1	Pathologic Constriction (Stenosis) 01/2021
1	Atherosclerotic Plaque (Atheroma) 01/2021
1	Critical Illness (Critically Ill) 01/2021
1	Gestational Weight Gain 01/2021
1	Neuroblastoma 01/2020
1	Hypertrophy 01/2019
1	ST Elevation Myocardial Infarction 09/2017
1	Mental Disorders (Mental Disorder) 10/2016
1	Trauma and Stressor Related Disorders 05/2016
1	Vascular Diseases (Vascular Disease) 06/2015
1	Ischemic Stroke 04/2015
1	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2013
1	Frontotemporal Dementia (Semantic Dementia) 10/2013
1	Huntington Disease (Huntington's Disease) 10/2013
1	Alzheimer Disease (Alzheimer's Disease) 10/2013
1	Acidosis 02/2013
1	Heart Failure 02/2013
1	Hyperoxia 02/2013

Drug/Important Bio-Agent (IBA)

8	Glutamic Acid (Glutamate)FDA Link 01/2019 - 11/2006
7	Ethanol (Ethyl Alcohol)IBA 01/2022 - 10/2006
5	Pharmaceutical PreparationsIBA 03/2017 - 02/2002
4	Serotonin (5 Hydroxytryptamine)IBA 01/2019 - 06/2006
4	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2015 - 11/2008
4	Haloperidol (Haldol)FDA LinkGeneric 01/2012 - 11/2008
3	Insulin (Novolin)FDA Link 04/2015 - 04/2008
3	Anti-Anxiety Agents (Anxiolytics)IBA 10/2014 - 12/2003
3	Hypnotics and Sedatives (Sedatives)IBA 05/2009 - 12/2006
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2013
2	Neurotransmitter Agents (Neurotransmitter)IBA 01/2019 - 10/2013
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2015 - 04/2015
2	TriazolesIBA 01/2015 - 02/2013
2	Proteins (Proteins, Gene)FDA Link 01/2015 - 12/2010
2	Peptides (Polypeptides)IBA 01/2015 - 02/2013
2	Antidepressive Agents (Antidepressants)IBA 01/2015 - 12/2003
2	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 10/2013 - 12/2010
2	Glutamate Receptors (Glutamate Receptor)IBA 10/2013 - 12/2009
2	Antipsychotic Agents (Antipsychotics)IBA 01/2012 - 11/2008
2	Aspartic Acid (Aspartate)FDA Link 05/2009 - 11/2008
2	Excitatory Amino Acid Transporter 1 (Glutamate Aspartate Transporter 1)IBA 05/2009 - 11/2008
2	Dizocilpine Maleate (Dizocilpine)IBA 05/2009 - 08/2008
2	LY 379268IBA 05/2009 - 11/2008
2	sphingosine kinaseIBA 04/2006 - 10/2005
2	NeuropeptidesIBA 11/2003 - 02/2002
1	Third Generation CephalosporinsIBA 01/2021
1	trimethyloxamine (trimethylamine N-oxide)IBA 01/2021
1	CalciumIBA 01/2021
1	Apolipoproteins E (ApoE)IBA 01/2021
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2021
1	Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric 01/2021
1	1-dodecylpyridoxal (PLD)IBA 01/2020
1	Biological ProductsIBA 01/2019
1	Acetylcysteine (Siran)FDA LinkGeneric 09/2017
1	Nitroglycerin (Dynamite)FDA LinkGeneric 09/2017
1	NitratesIBA 09/2017
1	EndocannabinoidsIBA 01/2017
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 10/2016
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 10/2016
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 04/2015
1	env Gene ProductsIBA 01/2015
1	Ketamine FDA LinkGeneric 01/2015
1	Kainic Acid (Kainate)IBA 10/2013
1	N-Methylaspartate (NMDA)IBA 10/2013
1	AcidsIBA 10/2013
1	Adrenergic Receptors (Adrenergic Receptor)IBA 02/2013
1	Isoproterenol (Isoprenaline)FDA LinkGeneric 02/2013
1	L 701324IBA 02/2013
1	Glycine Plasma Membrane Transport ProteinsIBA 02/2013
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 02/2013
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 02/2013
1	(R)- (N- (3- (4'- fluorophenyl)- 3- (4'- phenylphenoxy)propyl))sarcosineIBA 02/2013
1	Pentobarbital (Nembutal)FDA Link 02/2013
1	Serine (L-Serine)FDA Link 02/2013

Therapy/Procedure

5	Therapeutics 01/2020 - 12/2002
3	Hypnosis (Mesmerism) 07/2011 - 08/2008
2	Drug Therapy (Chemotherapy) 05/2016 - 11/2003
1	Radiotherapy 01/2022
1	Segmental Mastectomy (Lumpectomy) 01/2022
1	Advanced Trauma Life Support Care 10/2020
1	Percutaneous Coronary Intervention 09/2017